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cotD [2019-07-03 12:05:37]
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cotD [2019-07-03 12:05:37]

spore coat protein (inner)
locus
BSU22200
pI
7.37
mw
8.70 kDa
protein length
75 aa Sequence Blast
gene length
228 bp Sequence Blast
function
resistance of the spore
product
spore coat protein (inner)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.7|Class VI]

    • Gene

    Coordinates
    2,332,784 → 2,333,011

    The protein

    Protein family

  • nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)

    • [SW|Localization]

  • inner spore coat [Pubmed|19933362], localization depends on [protein|CEBEC9CECCF445C40D793E61A2CD23175631A473|SafA] [Pubmed|22171814]

    • Expression and Regulation

    Operons

    genes
    [gene|FA8D9AA0968365522DEFC05B277123FC96482044|cotD]
    description
    [Pubmed|22383849]

    sigma factors

  • [protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|15699190], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]

    • regulatory mechanism

  • [protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID]: repression, [Pubmed|7966271], in [regulon|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID regulon]
  • [protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE]: activation, [Pubmed|15383836], in [regulon|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE regulon]

    • regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigK], [SW|SpoIIID], [protein|search|GerE]) [Pubmed|15383836,15699190,7966271]
    • view in new tab

    genes
    [gene|4D286C045A43FBF0F6E93E9E46AD7F25E35ADA7C|mrfA]-[gene|3F1D78CAAA4B5057DEBB24C4D382F96DA4AA4852|mrfB]-[gene|FA8D9AA0968365522DEFC05B277123FC96482044|cotD]
    description
    [Pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • 1S104 ( ''cotD''::''cat''), [Pubmed|2821284], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S104&Search=1S104 BGSC]
  • BKE22200 (Δ[gene|FA8D9AA0968365522DEFC05B277123FC96482044|cotD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATAAAATCCCCTTTCC, downstream forward: _UP4_TAGTATGGAAAACGTGCAGC
  • BKK22200 (Δ[gene|FA8D9AA0968365522DEFC05B277123FC96482044|cotD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATAAAATCCCCTTTCC, downstream forward: _UP4_TAGTATGGAAAACGTGCAGC

    • References

    Reviews

  • 23202530

    • Original publications

  • 19933362,1518043,2821284,2492118,1691789,14651647,15699190,7966271,22171814,15383836